Research Associate/Senior Research Associate - Peptide/High Potent APIs (HPAPI)/Organic/Antibody Drug Conjugation (ADC)

SeniorOn-site
Companyo2h Group
LocationAhmedabad, Gujarāt, India
Category-
DepartmentChemistry
SenioritySenior
WorkplaceOn-site
Posted2026-07-21
Viarecruitee

Description

Peptide Chemist

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Plan and execute solid-phase and solution-phase peptide synthesis (SPPS/LPPS) using automated synthesizers such as Syro and CEM Liberty Blue

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Independently handle peptide synthesis across scales from gram to 1 kg, with troubleshooting abilities

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Purify and characterize peptides using preparative HPLC, analytical HPLC, LC-MS, and MS

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Operate, calibrate, and maintain lab equipment to keep synthesis workflows running smoothly

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Maintain compliance with laboratory safety and SHE (Safety, Health & Environment) standards

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Review relevant literature to inform synthetic strategy and troubleshooting approaches

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Keep accurate, timely experimental records (lab notebooks, batch records, ELN entries as applicable)

High Potent APIs (HPAPI)

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Perform hands-on laboratory chemistry activities involving high-potency APIs / potent compounds.

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Execute chemical reactions, work-ups, purification and related laboratory processes.

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Handle HPAPIs in accordance with applicable safety, containment and handling procedures.

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Maintain accurate laboratory records, experimental data and documentation.

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Support process development, optimization and troubleshooting activities.

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Perform analytical sample preparation and coordinate with analytical teams as required.

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Follow established GMP, EHS and laboratory safety requirements.

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Support investigation and resolution of laboratory/process-related issues.

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Where required, support chemistry activities related to ADC and highly potent payloads.

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Work effectively with cross-functional teams including analytical and other chemistry groups.

Organic Chemist

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Hands-on experience in performing chemical reactions from mg to gram scale independently under scientific guidance

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Strong knowledge of analytical and purification techniques, including NMR, Mass, HPLC, CombiFlash, and column chromatography

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Skilled in handling reaction setups, glassware assemblies, reagent charging, temperature control, and nitrogen operations

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Excellent documentation and data management practices with the ability to follow scientific procedures, patents, and experimental instructions accurately

Scaleup Chemist

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Experience in process R&D, scale-up synthesis, and purification from gm to kg scale

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Skilled in handling 50L/100L GLR assemblies and basic technology transfer activities

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Proficient in 1H NMR, HPLC, and LCMS interpretation

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Strong project execution and team collaboration skills

Antibody Drug Conjugation Chemist (ADC)

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Synthesis and purification of complex antibody drug conjugate (ADC) molecules

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Synthesis of different types of linkers – using natural and unnatural amino acids, PEGs

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Synthesis of highly potent drug molecules – payloads

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Purification of complex and large molecules by flash column and HPLC

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Handling various type chemistry with different payloads

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Interpretation and characterisation of higher molecular weight compounds