Scientist - DMPK
Description
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Perform routine in vitro ADME assays such as microsomal stability, plasma stability, solubility, permeability, CYP inhibition, and plasma protein binding assays
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Develop, optimise, and execute analytical methods using LC-MS/MS and complementary detection modalities (absorbance/fluorescence-based assays)
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Support development and validation of new ADME assays to expand the group’s scientific capabilities
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Process and analyse experimental data using GraphPad Prism, MS Excel, and mass spectrometry software platforms (e.g., Sciex)
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Prepare clear experimental documentation, study summaries, and reports for internal teams and external collaborators
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Coordinate with third-party collaborators for pharmacokinetic (PK) studies, including in vivo animal studies where applicable
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Present experimental results and scientific observations in internal meetings, project reviews, and cross-functional discussions
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Work closely with colleagues across biology, and ADME groups to provide integrated drug discovery support alongside chemistry teams
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Support laboratory operations including reagent ordering, inventory management, assay consumables tracking, and coordination of laboratory logistics