Manager, Clinical Stewardship Operations (RN)

Twin Health

At Twin Health, we empower people to improve and prevent chronic metabolic diseases, like type 2 diabetes and obesity, with a new standard of care. Twin Health is the only company applying AI Digital Twin technology exclusively toward metabolic health.

We start by building a dynamic model of each person’s metabolism — drawing on thousands of data points from CGMs, smartwatches, and meal logs — that maps their personal path to better health. Guided by a dedicated clinical care team, our members have lowered their A1C below the diabetes range, achieved lasting weight loss, and reduced or even eliminated medications, all while living healthier, happier lives.

Working here

Our team at Twin Health is passionate, talented, and united by a shared purpose: to improve the metabolic health and happiness of our members. We believe in empowering every Twin to make a meaningful impact for our members, our clients, and each other, while enjoying a supportive, collaborative work environment.

Twin has been recognized not only for our innovation but also for our culture, including: Innovator of the Year by the Employer Health Innovation Roundtable (EHIR), selected to CB Insights’ Digital Health 150, and named one of Newsweek’s Top Most Loved Workplace® .

With more than $100 million raised in recent funding, including a $53 million Series E round in 2025 led by Maj Invest, and a $50 million investment in 2023 led by Temasek, Twin is scaling rapidly across the U.S. and globally. Backed by leading venture firms like ICONIQ Growth, Sequoia, Sofina, Temasek, and Peak XV, we are building the most impactful digital health company in the world.

Join us as we reinvent the standard of care in metabolic health.

Opportunity

We are looking for a Registered Nurse and Manager, Clinical Stewardship Operations who is a self-starter energized by working with clients and building strong relationships both externally and internally to drive exceptional outcomes for our clients and members. In this role, you will own the implementation and deployment of Twin's stewardship programs end-to-end, bringing the clinical expertise needed to translate client goals into well-run, clinically sound programs. The ability to problem solve, analyze and troubleshoot, with strong verbal and written communication skills tailored to the situation and audience, will be key.

Working within a complex clinical delivery model in a high-growth environment, our Manager, Clinical Stewardship Operations has to expertly navigate ambiguity while managing internal and external teams in a detail-oriented, organized and structured manner, all while ensuring we deliver on time and exceed client expectations. As part of our small and growing team, you will be the clinical voice within Client Operations & Partnerships, and your input will be critical to helping Twin continuously improve, optimize and scale our stewardship implementations.

You should be a highly organized, client-focused and resourceful clinician. This role will be a great fit if you are a doer who is passionate about making a difference, comfortable with ambiguity, and naturally collaborative.

Responsibilities

Drive Client Value

• Establish and maintain highly effective relationships with key stakeholders, executives and clinical leaders across large enterprise clients, including health plans, health systems and PBMs

• Serve as the clinical subject matter expert for stewardship within Client Operations & Partnerships, providing clinical context to teammates, clients and internal partners

• Develop a fluent understanding of Twin Health programs, stewardship program mechanics, onboarding processes, ongoing program management and clinical operations

• Successfully implement stewardship programs end-to-end across a portfolio of Twin clients

• Lead discovery sessions to understand each client's clinical priorities, formulary and prescriber landscape, and goals in order to design tailored solutions that work for their populations

• Provide consultative recommendations to improve program results, strengthen member and provider engagement, and optimize overall client satisfaction

• Oversee the configuration, testing and validation of client-specific program logic to ensure clinical accuracy and proper functionality

• Coordinate internal resources and third parties/vendors for flawless execution of projects

• Analyze client data pre- and post-launch to provide clinical and operational insights that internal teams and clients can act on

Deliver Project Management Excellence

• Manage multiple complex stewardship implementations simultaneously, setting expectations, owning the overall project plan, and managing cross-functional teams to ensure timeliness and launch readiness

• Effectively manage client stakeholders throughout implementation, including leading client meetings, building alignment, and managing risks and escalations

• Work with client technical leads and third parties to operationalize data access and file management, including finalizing requirements, setting up file transfer and validation, and ongoing issue resolution

• Prepare presentations and reports in a consumable client format that delivers clear, usable insights post-launch

• Manage project expectations through regular meetings, status reports and strong relationships

• Build out standard implementation work plans, templates, playbooks and cross-functional SOPs to drive continuous improvement and best practices for stewardship

• Prepare, execute and participate in special events held for or hosted by clients

Lead Cross-functionally

• Manage client issues and escalations and mobilize internal teams such as Client Growth, Clinical Delivery, Product, Member Operations and Business Development to drive resolution

• Partner with Business Development and Client Growth on stewardship scoping, solutioning and new client opportunities, providing clinical input during the sales process

• Work cross-functionally with teams such as Clinical Delivery, Product, Marketing, Engineering, Billing Operations and Executive teams to ensure client and market feedback drives ongoing improvement

• Provide input and recommendations for internal process improvements that increase efficiency and effectiveness

• Serve as the internal SME and point person to ensure efficiency and consistency across the stewardship implementation lifecycle

• Drive internal alignment and manage cross-functional teams to ensure successful launches

• Other duties as assigned

Qualifications

• Registered Nurse (RN) required; BSN preferred

• 5+ years of combined clinical and non-clinical experience, including onboarding, program management and client-facing work

• Experience in a health plan, PBM, health system, digital health or care management setting

• Experience with health benefits, health and wellness, health plans or health systems

• Ability to communicate and work across client organizations, engaging on both tactical and strategic issues, with senior executives as well as execution teams

• Exceptionally strong project management skills, with demonstrated organization, attention to detail, and the ability to balance thoughtful planning with timely execution

• Ability to manage conflicting priorities and thrive in a fast-paced environment under time constraints

• Proficiency with Google applications and PM tools such as Monday.com and MS Project

• Experience working with technical and data teams (internal and external) on data exchange, file specifications, encryption, transmission and testing

Preferred

• Background in medication management, such as pharmacy-related programs, formulary or utilization management, or prescriber engagement

• Experience with GLP-1 therapies, including clinical management, access, or program design

• Experience with chronic disease or metabolic care

• PMP or similar certification

• Prior people management experience

• This remote